Blend-Cleaver-Mini

A modular fusion enzyme that lands on plastic and teams a mini-PETase with a broad polyester esterase to depolymerize PET blends and adhesive-laminates.

Project Overview

Using AlphaFold, I designed a modular fusion enzyme to break down PET blends and adhesive-laminates.

Features

Modular design allows for easy modification of the enzyme.
Ready to be used in a lab setting.
Can be used to break down PET blends and adhesive-laminates.
Targets multiple types of plastic, using its dual catalysis

What I learned

How to use AlphaFold to design an enzyme.
How to use the Protein Data Bank to find relevant enzymes.
Building a protein structure from scratch.
How to read pLDDT, pTM, PAE.

Read the findings article

Article - BCM Initial Findings

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